Invitrogen™ SNAP alpha Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583808

Product Code. 16320765

Description

Immunogen sequence: IEEACEIYAR AANMFKMAKN WSAAGNAFCQ AAQLHLQLQS KHD Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.

SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.

Specifications

• Antigen: SNAP alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NAPA
• Gene Alias: 1500039N14Rik; alpha snap; alpha soluble NSF attachment protein; alpha-SNAP; Alpha-soluble NSF attachment protein; a-SNAP; AW209189; hydrocephaly with hop gait; hyh; Napa; N-ethylmaleimide sensitive fusion protein attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; NSF attachment protein alpha; RA81; Snap; SNAPA; SNAP-alpha; SNARE
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8775
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P54920
• Gene Symbols: NAPA
• Immunogen: Recombinant protein corresponding to Human NAPA. Recombinant protein control fragment (Product #RP-98823).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG