SNAP 94847 hydrochloride, Tocris Bioscience™

Description

Potent and selective MCH1 antagonist

Potent melanin-concentrating hormone receptor 1 (MCH1) antagonist (Ki = 2.2 nM, KD = 530 pM) that displays > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Increases neurogenesis in the dentate gyrus and decreases food-reinforced operant responding in vivo. Exhibits anxiolytic activity and is orally active.

Specifications

• CAS: 487051-12-7
• Molecular Formula: C29H33ClF2N2O2
• Quantity: 10mg
• Synonym: snap 94847 hydrochloride, n-3-1-4-3,4-difluorophenoxy phenyl methyl-4-piperidinyl-4-methylphenyl-2-methylpropanamide hydrochloride
• InChI Key: DEDUDFNRQKUBRH-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C=C1)NC(=O)C(C)C)C2CCN(CC2)CC3=CC=C(C=C3)OC4=CC(=C(C=C4)F)F.Cl
• IUPAC Name: N-[3-[1-[[4-(3,4-difluorophenoxy)phenyl]methyl]piperidin-4-yl]-4-methylphenyl]-2-methylpropanamide;hydrochloride
• Molecular Weight (g/mol): 515.042
• PubChem CID: 56972235
• Formula Weight: 515.03
• Percent Purity: >98%
• Chemical Name or Material: SNAP 94847 hydrochloride