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Invitrogen™ SNAIL Monoclonal Antibody (6D2)

Product Code. 12857812
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Quantity:
100 μL
Unit Size:
100µL
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12857812 100 μL 100µL
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Product Code. 12857812 Supplier Invitrogen™ Supplier No. MA515791

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Description

Mouse Monoclonal Antibody

MA5-15791 targets SNAI1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15791 immunogen is purified recombinant fragment of human SNAI1 expressed in E. Coli. MA5-15791 detects SNAI1 which has a predicted molecular weight of approximately 29kDa.

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNAIL
Applications ELISA, Western Blot
Classification Monoclonal
Clone 6D2
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene Snai1
Gene Accession No. O95863
Gene Alias AI194338; dJ710H13.1; Protein sna; protein snail homolog 1; SLUGH2; SNA; Sna protein; Sna1; SNAH; snai; SNAI1; Snail; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
Gene Symbols Snai1
Host Species Mouse
Immunogen Purified recombinant fragment of human SNAI1 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6615
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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