Invitrogen™ SMOX Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561432

Product Code. 15719251

Description

Immunogen sequence: QGFTDVTVLE ASSHIGGRVQ SVKLGHATFE LGATWIHGSH GNPIYHLAEA NGLLEETTDG ERSVGRISLY SKNGVACYLT NHGRRIPKDV VEEFSDLYN Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 98%.

Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates.

Specifications

• Antigen: SMOX
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMOX
• Gene Alias: B130066H01Rik; C20orf16; flavin containing amine oxidase; flavin-containing spermine oxidase; PAO; PAO1; PAO-1; PAOH; PAOh1; Polyamine oxidase 1; putative cyclin G1 interacting protein; SMO; Smox; Spermine oxidase; UNQ3039/PRO9854
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54498
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NWM0
• Gene Symbols: SMOX
• Immunogen: Recombinant protein corresponding to Human SMOX. Recombinant protein control fragment (Product #RP-99298).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG