Smooth Muscle Myosin, clone: SMMS-1, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-6400-82
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: This SMMS-1 monoclonal antibody reacts with both isoforms of the human smooth muscle myosin heavy chain (SM1 and SM2) structural proteins, which are components of the contractile apparatus in smooth muscle cells. Smooth muscle myosin heavy chains are expressed by myoepithelial cells and also serve as the terminal differentiation marker for smooth muscle cells. In normal breast tissue, myoepithelial cells compose the outer layer of the lumen lining. In benign and in situ breast lesions, the intact myoepithelial layer stains with SMMS-1 and the loss of this staining indicates invasive cancer. This SMMS-1 antibody has also been reported to cross-react with bovine, canine, feline, and rat smooth muscle myosin heavy chains.Applications Reported: This SMMS-1 antibody has been reported for use in western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This SMMS-1 antibody has been tested by western blot on rat heart and immunohistochemistry on formalin-fixed paraffin embedded tissue (with IHC Antigen Retrieval Solution - Low pH (cat. 00-4955)). This can be used at less than or equal to 5 ug/mL. It is recommended that the antibody be titrated for optimal perfomance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|Smooth Muscle Myosin|
|PBS with 0.09% sodium azide; pH 7.2|
|myosin heavy chain 11, myosin heavy chain, smooth muscle isoform, myosin, heavy polypeptide 11, smooth muscle, myosin-11|
|Store at 2-8°C.|
For Research Use Only.