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Invitrogen™ SMN1 Monoclonal Antibody (2F1)

Product Code. 12807882
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
12807882 100 μL 100µL
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Product Code. 12807882 Supplier Invitrogen™ Supplier No. MA515857

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Description

Mouse Monoclonal Antibody

MA5-15857 targets SMN1 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human and Non-human primate samples. The MA5-15857 immunogen is purified recombinant fragment of human SMN1 expressed in E. Coli. . MA5-15857 detects SMN1 which has a predicted molecular weight of approximately 39kDa.

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMN1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 2F1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene SMN1
Gene Accession No. Q16637
Gene Alias AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A
Gene Symbols SMN1
Host Species Mouse
Immunogen Purified recombinant fragment of human SMN1 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6606
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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