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Smilagenin, MedChemExpress

Product Code. 16470437
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Product Code. 16470437 Supplier Medchem Express Supplier No. HY106353

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Description

MedChemExpress Smilagenin (SMI) is a small-molecule steroidal sapogenin from Rhizoma anemarrhenae and Radix asparagi widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases.

Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density. Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD.

Specifications

Chemical Name or Material Smilagenin
CAS 126-18-1
Color White
Purity Grade Notes Research
Molecular Formula C27H44O3
Quantity 50 mg
Solubility Information Ethanol : ≥ 10 mg/mL (24.00 mM) ∣DMSO : 5 mg/mL (12.00 mM; Need ultrasonic)
SMILES C[C@@H]1[C@@]2(CC[C@@H](C)CO2)O[C@]3([H])[C@@]1([H])[C@@]4([C@@]([C@@]5([H])[C@]([C@@]6([C@](C[C@@H](O)CC6)([H])CC5)C)([H])CC4)([H])C3)C
Molecular Weight (g/mol) 416.64
Formula Weight 416.64
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
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Research purposes only

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