Invitrogen™ SMC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110399

Product Code. 17178323

Description

Immunogen sequence: EELAGLKNTA EKYRQLKQQW EMKTEEADLL QTKLQQSSYH KQQEELDALK KTIEESEETL KNTKEIQRKA EEKYEVLENK MKNAEAERER ELKDAQKKLD CAKTKADASS KKMKEKQQEV EAITLELEEL KREHTSYKQQ LEAVNEAIKS YESQIEVMAA EVAKNKESVN KAQEEVTKQK EVITAQDTVI KAKYAEVAKH K.

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.

Specifications

• Antigen: SMC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMC2
• Gene Alias: 5730502P04Rik; AI255214; AW545314; CAP E; CAPE; CAP-E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; Fin16; FLJ10093; hCAP-E; PRO0324; SMC protein 2; Smc2; SMC-2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; Smc2l1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; structural maintenance of chromosomes 2; structural maintenance of chromosomes protein 2; XCAP-E homolog
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10592, 14211
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.66 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O95347, Q8CG48
• Gene Symbols: SMC2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 700-900 of human SMC2 (NP_006435.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG