Invitrogen™ SMARCA5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596029

Product Code. 16538871

Description

Immunogen sequence: ELFAHFIQPA AQKTPTSPLK MKPGRPRIKK DEKQNLLSVG DYRHRRTEQE EDEELLTESS KATNVCTRFE DSPSYVKWGK LRDYQVRGLN WLISLYENGI NGILADEMGL GKTLQTISLL GYMKHYRNIP GPHMVLVPKS TLHNWMSEFK RWVPTLRSVC LIGDKEQRAA FVRDVLLPGE WDVCVTSYEM LIKEKSVFKK FNWRYLVIDE AHRIKNEKSK LSEIVREFKT TNRLLLTGTP LQNNLHELWS LLNFLLPDVF NSADDFDSWF DTNNCLGDQK LVERLHMVLR PFLLRRIKAD V; Positive Samples: PC-3, H460, 293T, HepG2, SH-SY5Y, Mouse spleen, Mouse brain, Mouse testis; Cellular Location: Nucleus.

SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.

Specifications

• Antigen: SMARCA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMARCA5
• Gene Alias: 4933427E24Rik; D030040M08Rik; D330027N15Rik; hISWI; hSNF2H; ISWI; MommeD4; mSnf2h; SMARCA5; SNF2H; sucrose nonfermenting protein 2 homolog; sucrose nonfermenting-like 5; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; WCRF135
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8467, 93762
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.24 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60264, Q91ZW3
• Gene Symbols: SMARCA5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human SMARCA5/SNF2H (NP_0035923).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG