Invitrogen™ SLMAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551708

Product Code. 15779660

Description

Immunogen sequence: SEYEKEITSL QNSFQLRCQQ CEDQQREEAT RLQGELEKLR KEWNALETEC HSLKRENVLL SSELQRQEKE LHNSQKQSLE LTSDLSILQM SRKELENQVG SLKEQHLRDS ADLKTLLSKA ENQAKDVQKE YEKTQTVLSE LKLKFEMTEQ Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 91%.

Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.

Specifications

• Antigen: SLMAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slmap
• Gene Alias: D330001L02Rik; KIAA1601; mKIAA1601; sarcolemma associated protein; sarcolemmal membrane-associated protein; Sarcolemmal-associated protein; Slap; Slmap; UNQ1847/PRO3577
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290533, 7871
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P0C219, Q14BN4
• Gene Symbols: Slmap
• Immunogen: Recombinant protein corresponding to Human SLMAP. Recombinant protein control fragment (Product #RP-102135).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG