Invitrogen™ SLC5A5 Monoclonal Antibody (14F), APC

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA545489

Product Code. 17886442

Description

1 μg/mL of MA5-45489 was sufficient for detection of hNIS in 20 μg of transfected COS-7 cell membrane lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 97kDa, non-glycosylated version at 68kDa. Other minor bands associated with hNIS at 160kDa, and degradation products at approximately 30 kDa, and approximately 15kDa.

Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.

Specifications

• Antigen: SLC5A5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.46mM phosphate with 2mM EDTA and no preservative; pH 7.4
• Gene Accession No.: Q63008, Q92911, Q99PN0
• Gene Symbols: SLC5A5
• Immunogen: Mannose binding protein hNIS fusion (AA468-643).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (PFA fixed), Western Blot, Microarray
• Clone: 14F
• Conjugate: APC
• Gene: SLC5A5
• Gene Alias: Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Nis; SLC5A5; sodium iodide symporter; Sodium/iodide cotransporter; sodium-iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; solute carrier family 5 member 5; solute carrier family 5, member 5; TDH1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 114479, 114613, 6528
• Content And Storage: 4°C
• Form: Liquid