Invitrogen™ SLC4A8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5101904

Product Code. 16688374

Description

Antibody detects endogenous levels of total SLC4A8/10.

Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Specifications

• Antigen: SLC4A8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc4a8
• Gene Alias: AW493845; C230026C11; Electroneutral Na(+)-driven Cl-HCO3 exchanger; electroneutral Na+-driven Cl-HCO3 exchanger; Electroneutral sodium bicarbonate exchanger 1; KIAA0739; k-NBC3; kNBC-3; Na-driven Cl-HCO3 exchanger NDCBE1-A; Na-driven Cl-HCO3 exchanger NDCBE1-B; Na-driven Cl-HCO3 exchanger NDCBE1-C; NBC; NBC3; NDCBE; NDCBE1; RGD:735164}; Slc4a8; slc4a8 {ECO:0000312; sodium bicarbonate cotransporter isoform 3 kNBC-3; solute carrier family 4 (anion exchanger), member 8; solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 315311, 59033, 9498
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q2Y0W8, Q6RVG2, Q8JZR6
• Gene Symbols: Slc4a8
• Immunogen: A synthesized peptide derived from human SLC4A8(Accession Q2Y0W8), corresponding to amino acid residues F1040-S1090.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG