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Invitrogen™ SLC39A2 Polyclonal Antibody

Product Code. 12839212
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Quantity:
100 μg
Unit Size:
100µg
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12839212 100 μg 100µg
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Product Code. 12839212 Supplier Invitrogen™ Supplier No. PA521067

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Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-21067 can be used with blocking peptide PEP-1181.

The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC39A2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SLC39A2
Gene Accession No. Q9NP94
Gene Alias 6A1; ETI-1; F730005G13Rik; Gm1789; Gm289; MGC119190; SLC39A2; solute carrier family 39 (zinc transporter), member 2; solute carrier family 39 member 2; Zinc transporter ZIP2; zinc uptake transporter 2; ZIP2; ZIP-2; Zrt- and Irt-like protein 2
Gene Symbols SLC39A2
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of human ZIP2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 214922, 29986, 305846
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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