SLC34A1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA562358

Product Code. 15760152

Description

Immunogen sequence: PLPVPGGHVM RGTAFAYVPS PQVLHRIPGT SAYAFPSLGP VALAEHTCPC GEVLERHEPL PAKLALEEEQ KPESRLVPKL RQA Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 73%.

Renal tubular reabsorption of phosphate is critical to the maintenance of phosphate homeostasis in mammals. The brush-border membrane Na+/Pi cotransport systems in proximal tubules play a major role in this process. The renal Na(+)/P(i) cotransporter NPT2 is expressed in the brush border membrane (BBM) of proximal tubular cells. NPT2 gene expression is crucial for PTH effects on renal P(i) handling. However, renal expression of the sodium/phosphate cotransporter gene, NPT2, is not required for regulation of renal 1 alpha-hydroxylase by phosphate. NPT2 is an integral membrane protein expressed in kidney and lung. The gene encoding human NPT1 maps to chromosome 6q21.3-p23, while the gene encoding human NPT2 maps to chromosome 5q35.

Specifications

• Antigen: SLC34A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC34A1
• Gene Alias: FRTS2; HCINF2; Na(+)/Pi cotransporter 2A; Na(+)-dependent phosphate cotransporter 2A; Na/Pi cotransporter; Na+-phosphate cotransporter type II; NaPi-2; NaPi2A; naPi-2a; NAPI-3; naPi-7; NaPi-IIa; NPHLOP1; NPT2; Npt2a; NPTIIa; renal Na+/Pi transporter; renal sodium-dependent phosphate transporter; SLC11; Slc17a2; Slc34a1; sodium/phosphate co-transporter; sodium/phosphate cotransporter 2A; Sodium-dependent phosphate transport protein 2A; sodium-phosphate transport protein 2A; solute carrier family 17 (sodium phosphate), member 2; solute carrier family 17 (sodium/hydrogen exchanger) member 2; solute carrier family 17 (sodium/hydrogen exchanger), member 2; solute carrier family 34 (sodium phosphate), member 1; solute carrier family 34 (type II sodium/phosphate cotransporter), member 1; solute carrier family 34 member 1; solute carrier family 34, member 1; type IIa Na+/Pi-cotransporter
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6569
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q06495
• Gene Symbols: SLC34A1
• Immunogen: Recombinant protein corresponding to Human SLC34A1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only