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SLC22A18 Polyclonal Antibody, Invitrogen™

Product Code. 15585671
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Quantity:
100 μg
Unit Size:
100µg
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15585671 100 μg 100µg
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Product Code. 15585671 Supplier Invitrogen Supplier No. PA538761

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Description

Rabbit Polyclonal Antibody

ORCTL2 (organic cation transporter-like protein 2), also known as HET, ITM, BWR1A, IMPT1, TSSC5, BWSCR1A, SLC22A1L, p45-BWR1A or SLC22A18, is a 424 amino acid multi-pass membrane protein that localizes at the apical membrane surface of renal proximal tubules. ORCTL2 is expressed at high levels in the kidney, liver, colon and in fetal renal proximal tubules and present at lower levels in heart, brain and lung. Belonging to the major facilitator superfamily, ORCTL2 may act as a transporter of organic cations based on a proton efflux antiport mechanism and may also play a role in the transport of chloroquine and quinidine-related compounds in kidney. Defects in ORCTL2 are associated with breast and lung cancer and are the cause of rhabdomyosarcoma type 1, a maligt tumor derived from striated muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC22A18
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SLC22A18
Gene Accession No. Q96BI1
Gene Alias Solute carrier family 22 member 18, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein, Efflux transporter-like protein, Imprinted multi-membrane-spanning polyspecific transporter-related protein 1, Organic cation transporter-like protein 2, ORCTL-2, Solute carrier family 22 member 1-like, Tumor-suppressing STF cDNA 5 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein, p45-Beckwith-Wiedemann region 1 A, p45-BWR1A, SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5
Gene Symbols SLC22A18
Host Species Rabbit
Immunogen A synthetic peptide derived from the C-terminal region of human ORCTL-2
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5002
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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