Invitrogen™ SLC19A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588778

Product Code. 16576891

Description

Immunogen sequence: LDGLRHCQRG HHPRQPPAQG LRSAAEEKAA QALSVQDKGL GGLQPAQSPP LSPEDSLGAV GPASLEQRQS DPYLAQAPAP QAAEFLSPVT TPSPCTLCSA QASGPEAADE TCPQLAVHPP GVSKLGLQCL PSDGVQNVNQ; Positive Samples: HeLa, U-87MG; Cellular Location: Membrane, Multi-pass membrane protein.

Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.

Specifications

• Antigen: SLC19A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC19A1
• Gene Alias: AI323572; CHMD; FLOT1; folate transporter 1; FOLT; IFC1; IFC-1; Intestinal folate carrier 1; intestinal folate carrier protein; methotrexate carrier 1; methotrexate carrier 2; methotrexate carrier 5; methotrexate carrier 6; MTX1; MTX-1; Placental folate transporter; reduced folate carrier 1; Reduced folate carrier protein; Reduced folate transporter; Reduced folate transporter 1; REFC; RFC; RFC1; RFC-1; RFT-1; SLC19A1; solute carrier family 19 (folate transporter), member 1; solute carrier family 19 (sodium/hydrogen exchanger), member 1; solute carrier family 19 member 1; solute carrier family 19, member 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6573
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P41440
• Gene Symbols: SLC19A1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 452-591 of human SLC19A1 (NP_9192311).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG