Invitrogen™ SLC10A7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA537058

Product Code. 15564221

Description

This antibody detects endogenous protein at a molecular weight of 39 kDa. Purity is >95% by SDS-PAGE.

SLC10A7 (solute carrier family 10 (sodium/bile acid cotransporter family), member 7), also known as P7, is a 358 amino acid multi-pass membrane protein belonging to the sodium:bile acid symporter family. Existing as seven alternatively spliced isoforms, SLC10A7 is expressed at high levels in liver and lung, moderate levels in placenta, kidney, spleen, and thymus, and low levels in heart, prostate, and testis. A few members of the sodium:bile acid symporter family, such as NTCP (also known as SLC10A1) and Asbt (also known as SLC10A2), are involved in maintaining enterohepatic circulation of bile acids by mediating the first step of active bile transport through membrane barriers of liver and intestine. Other family members, including SLC10A6, play an important role in the cellular delivery of specific prohormones in testis, placenta, adrenal gland and other peripheral tissues. Orphan carriers such as SLC10A7 are uncharacterized and their functions unknown.

Specifications

• Antigen: SLC10A7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC10A7
• Gene Alias: 2410193C02Rik; C4orf13; Na(+)/bile acid cotransporter 7; P7; PSEC0051; SBF-domain containing protein; SLC10A7; Sodium/bile acid cotransporter 7; solute carrier family 10 (sodium/bile acid cotransporter family), member 7; solute carrier family 10 (sodium/bile acid cotransporter family), member 7-like; solute carrier family 10 member 7; solute carrier family 10, member 7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 291942, 76775, 84068
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q0GE19, Q5PT50, Q5PT53
• Gene Symbols: SLC10A7
• Immunogen: Synthetic peptide corresponding to amino acids 212-257 of human SLC10A7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG