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Skeletal Muscle Actin Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1)), Invitrogen™

Product Code. 11344663
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Quantity:
500 μL
Unit Size:
500µL
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11344663 500 μL 500µL
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Product Code. 11344663 Supplier Invitrogen Supplier No. MA512542

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Description

Mouse Monoclonal Antibody

MA5-12542 targets Actin Skeletal Muscle in IF and IHC (P) applications and shows reactivity with Amphibian, Bovine, Guinea Pig, Human, Ovine, Rabbit, and Rat samples. The MA5-12542 immunogen is n-terminal decapeptide.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Skeletal Muscle Actin
Applications Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 5C5.F8.C7 (alpha-Sr-1)
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Acta1
Gene Accession No. P62736, P62737, P62738, P62739, P62740, P68133, P68134, P68135, P68136, P68138
Gene Alias 0610041G09Rik; AA959943; AAT6; ACTA; Acta1; ACTA1 protein; Acta2; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Acts; ACTSA; Actsk-1; Actvs; alpha actin; alpha actin 2; Alpha-actin-1; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-smooth muscle actin; ASMA; a-SMA; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; GIG46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; LOW QUALITY PROTEIN: actin, aortic smooth muscle; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; SMalphaA; smooth muscle alpha-actin; unnamed protein product
Gene Symbols Acta1, ACTA2
Host Species Mouse
Immunogen N-terminal decapeptide
Purification Method Ammonium sulfate precipitation
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009271, 100009506, 100716933, 100722917, 101107662, 101121051, 11459, 11475, 281592, 29437, 515610, 58, 59, 81633
Target Species Amphibian, Bovine, Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgM κ
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