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Tocris™ SK 609

Product Code. 18749446
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5 mg
25 mg
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25mg
5mg
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18749446 25 mg 25mg
18729636 5 mg 5mg
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Product Code. 18749446 Supplier Tocris™ Supplier No. 7039/25
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Estimated Shipment: 31-07-2026
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Dopamine D3 receptor biased agonist

SK 609 is a dopamine D3 receptor biased agonist. Preferentially signals via the G protein-dependent pathway (EC50 values for G protein and β-arrestin-dependent signaling are 1.1 and 50.2 μM, respectively). Exhibits selectivity for D3 over D2 receptors. Improves motor deficits in rodent Parkinson's disease models and ameliorates L-DOPA (Cat. No. 3788) induced abnormal involuntary movements.
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Specifications

Chemical Name or Material 2-chloro-α-methyl-benzenepropanamine hydrochloride
CAS 1092797-77-7
Quantity 25 mg
Target Dopamine D3 Receptor Agonists
Molecular Formula C10H14ClN.HCl
Formula Weight 3333
Purity 98%
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