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  8. Sivelestat sodium, MedChemExpress

Sivelestat sodium, MedChemExpress

Product Code. 16437348
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Product Code. 16437348 Supplier Medchem Express Supplier No. HY17443A

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Description

MedChemExpress Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Specifications

Chemical Name or Material Sivelestat sodium
CAS 150374-95-1
Color White
Purity Grade Notes Research
Molecular Formula C20H21N2NaO7S
Quantity 10 mg
Synonym ONO5046-Na Sodium sivelestat EI546 sodium LY544349 sodium
Solubility Information DMSO : 100 mg/mL (219.09 mM; Need ultrasonic) ∣H2O : 1 mg/mL (2.19 mM; ultrasonic and warming and heat to 80°C)
SMILES CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O[Na])=O)=O)=O)C=C1)=O
Molecular Weight (g/mol) 456.44
Formula Weight 456.44
Percent Purity 99.13%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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