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Sivelestat, MedChemExpress
Description
Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
Specifications
Specifications
| Chemical Name or Material | Sivelestat |
| CAS | 127373-66-4 |
| Color | Off-White |
| Purity Grade Notes | Research |
| Molecular Formula | C20H22N2O7S |
| Quantity | 50 mg |
| Synonym | EI546 LY544349 ONO5046 |
| Solubility Information | DMSO : ≥ 100 mg/mL (230.17 mM) ∣Ethanol : 3.03 mg/mL (6.97 mM; Need ultrasonic) |
| SMILES | CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O)=O)=O)=O)C=C1)=O |
| Molecular Weight (g/mol) | 434.46 |
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Research purposes only
Product Title
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