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Sivelestat, MedChemExpress

Product Code. 16443367
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 16443367

Brand: Medchem Express HY17443

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Description

MedChemExpress Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Specifications

Chemical Name or Material Sivelestat
CAS 127373-66-4
Color Off-White
Purity Grade Notes Research
Molecular Formula C20H22N2O7S
Quantity 50 mg
Synonym EI546 LY544349 ONO5046
Solubility Information DMSO : ≥ 100 mg/mL (230.17 mM) ∣Ethanol : 3.03 mg/mL (6.97 mM; Need ultrasonic)
SMILES CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O)=O)=O)=O)C=C1)=O
Molecular Weight (g/mol) 434.46
Formula Weight 434.46
Percent Purity 98.26%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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