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SIRT5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16894154 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16894154 20 μL 20µL
16884154 150 μL 150µL
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Product Code. 16894154

Brand: Proteintech 151221AP20UL

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This item is not returnable. View return policy

Rabbit Polyclonal Antibody

SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.

Specifications

Antigen SIRT5
Applications Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SIRT5
Gene Accession No. Q68FX9, Q8K2C6, Q9NXA8
Gene Alias SIR2 like protein 5, SIR2L5, SIRT5
Gene Symbols Sirt5
Host Species Rabbit
Immunogen SIRT5 Fusion Protein Ag7195
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23408, 306840, 68346
Target Species Rat, Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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