SIRT3 Mouse anti-Human, Clone:6C12D1, Abnova™

Mouse monoclonal antibody raised against recombinant human SIRT3.

Brand:  Abnova MAB17164.100ug

Product Code. 16034606

Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq]

Specifications

• Antigen: SIRT3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry
  Immunocytochemistry
  Flow Cytometry
  The optimal working dilution should be determined by the end user.
• Gene: SIRT3
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 6C12D1
• Description: sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: SIR2L3
• Immunogen: Recombinant protein corresponding to amino acid 155-290 of human SIRT3 from E. coli.
• Gene ID (Entrez): 23410
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid