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Invitrogen™ SIRT2 Polyclonal Antibody

Product Code. 12808672
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12808672 100 μg 100µg
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Product Code. 12808672 Supplier Invitrogen™ Supplier No. PA520490

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20490 can be used with blocking peptide PEP-0610.

The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIRT2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SIRT2
Gene Accession No. Q5RJQ4, Q8IXJ6, Q8VDQ8
Gene Alias 5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2
Gene Symbols SIRT2
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of the human SIRT2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22933, 361532, 64383
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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