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Invitrogen™ SIPA1L3 Polyclonal Antibody

Product Code. 12848972
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Quantity:
100 μg
Unit Size:
100µg
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12848972 100 μg 100µg
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Product Code. 12848972 Supplier Invitrogen™ Supplier No. PA520849

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Description

Rabbit Polyclonal Antibody

A suggested positive control is SK-N-SH cell lysate. PA5-20849 can be used with blocking peptide PEP-0963.

Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIPA1L3
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SIPA1L3
Gene Accession No. G3X9J0, O60292
Gene Alias 2610511M17Rik; CTRCT45; KIAA0545; signal induced proliferation associated 1 like 3; signal-induced proliferation-associated 1 like 3; signal-induced proliferation-associated 1-like protein 3; Sipa1l3; SIPA1-like protein 3; SPA-1-like 3; SPA-1-like protein 3; Spal3; SPAR3
Gene Symbols SIPA1L3
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the amino terminus of human SIPA1L3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23094, 292771, 74206
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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