SIPA1L2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520848

Product Code. 12828972

Description

A suggested positive control is rat brain tissue lysate. PA5-20848 can be used with blocking peptide PEP-0962.

Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.

Specifications

• Antigen: SIPA1L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIPA1L2
• Gene Alias: BC058408; Kiaa0545; KIAA1389; mKIAA1389; serine-rich synapse associated protein 2; serine-rich synapse-associated protein; Sersap2; signal induced proliferation associated 1 like 2; signal-induced proliferation-associated 1 like 2; signal-induced proliferation-associated 1-like protein 2; Sipa1l2; SIPA1-like protein 2; SPA-1-like 2; SPAL2; Spar2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 244668, 361442, 57568
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q5JCS6, Q80TE4, Q9P2F8
• Gene Symbols: SIPA1L2
• Immunogen: A 19 amino acid peptide from near the amino terminus of human SIPA1L2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG