Invitrogen™ SIM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5113657

Product Code. 17171514

Description

Immunogen sequence: MKEKSKNAAR TRREKENSEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis, it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.

Spécification

• Antigen: SIM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIM1
• Gene Alias: BHLHE14; bHLH-PAS transcription factor; Class E basic helix-loop-helix protein 14; mSIM1; SIM bHLH transcription factor 1; SIM bHLH transcription factor 1a; sim1; sim1a; single-minded 1; single-minded family bHLH transcription factor 1; single-minded family bHLH transcription factor 1a; single-minded homolog 1; single-minded homolog 1 (Drosophila); single-minded homolog 1-A; single-minded-like 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6492
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P81133
• Gene Symbols: SIM1
• Immunogen: Synthetic peptide directed towards the N terminal region of human SIM1 (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG