Invitrogen™ Sigma-1 Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530372

Product Code. 13444867

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (94%), Rat (96%), Rhesus Monkey (100%), Bovine (97%), Guinea pig (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

Specifications

• Antigen: Sigma-1 Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIGMAR1
• Gene Alias: AAG8; Aging-associated gene 8 protein; AL024364; ALS16; DSMA2; hSigmaR1; mSigmaR1; opioid receptor, sigma 1; Oprs1; RP23 167I12.6; SIG 1R; SIG-1R; sigma 1 receptor variant SR-1D; sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; sigma1 receptor; Sigma-1 Receptor; sigma1R; sigma1-receptor; Sigmar1; SR BP; SR31747 binding protein 1; SR31747-binding protein; SRBP; SR-BP; SR-BP1; zgc:56378
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10280, 18391, 393952
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.24 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O55242, Q7ZWG9, Q99720
• Gene Symbols: SIGMAR1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SIGMAR1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Zebrafish
• Product Type: Antibody
• Isotype: IgG