SIGLEC9 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13377-1-AP-20UL

Product Code. 16841554

Description

Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- andNK cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation with mucins in an epithelial cancer patient.

Specifications

• Antigen: SIGLEC9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIGLEC9
• Gene Alias: CD329, CDw329, OBBP LIKE, Protein FOAP 9, Siglec 9, SIGLEC9
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27180, 83382
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Concentration: 0.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9Y336
• Gene Symbols: SIGLEC9, Siglece
• Immunogen: SIGLEC9 Fusion Protein Ag4201
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG