Invitrogen™ SIGLEC16 Monoclonal Antibody (706030)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561723

Product Code. 30534562

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

SIGLEC16 (Sialic Acid Binding Ig Like Lectin 16) is a gene that encodes a member of the Siglec family of proteins, which are primarily expressed on the surface of immune cells such as macrophages, dendritic cells, and certain types of lymphocytes. These proteins are involved in the recognition of sialic acid-containing glycan structures on the surface of cells, playing a crucial role in cell-cell interactions and immune regulation. SIGLEC16, in particular, is thought to participate in modulating immune responses and maintaining immune homeostasis. It can influence processes such as inflammation, phagocytosis, and the inhibition of immune cell activation. The expression and function of SIGLEC16 can vary among individuals due to genetic polymorphisms, which may impact susceptibility to infections and autoimmune diseases. Understanding the specific roles and mechanisms of SIGLEC16 in immune regulation is important for developing therapeutic strategies aimed at modulating immune responses in various diseases, including inflammatory and autoimmune conditions. Research into SIGLEC16 also provides insights into the broader functions of the Siglec family and their potential as targets for immunotherapy.

Specifications

• Antigen: SIGLEC16
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Immunogen: Human Siglec-16 peptide.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Flow Cytometry
• Clone: 706030
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1