Invitrogen™ SIDT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557435

Product Code. 15755331

Description

Immunogen sequence: SFGSNDGSGN MVASHPIAAS TPEGSNYGTI DESSSSPGRQ MSSSDGGPPG QSDTDSSVEE SDFDTMPDIE SDKNIIRTKM FLYLSDLSRK DRRIV Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.

The SIDT1 gene encodes the SID1 transmembrane family member 1 protein, which is involved in RNA transport and may play a role in RNA silencing pathways. SIDT1 has been studied for its role in facilitating the uptake and cellular exchange of double-stranded RNA (dsRNA), a process that is crucial for gene regulation and immune responses. The protein's activity is thought to be involved in RNA interference (RNAi), a mechanism for silencing genes that are complementary to an introduced dsRNA. SIDT1's function is important for maintaining RNA homeostasis and regulating gene expression, impacting various cellular processes and potential therapeutic applications, such as antiviral strategies and cancer treatment. Understanding the role of SIDT1 in RNA transport and the RNAi pathway provides insights into how cells manage genetic and environmental information, which could be pivotal for developing RNA-based therapeutic interventions.

Specifications

• Antigen: SIDT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIDT1
• Gene Alias: AW045928; B830021E24Rik; SID1; SID-1; SID1 transmembrane family member 1; SID1 transmembrane family, member 1; SIDT1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54847
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NXL6
• Gene Symbols: SIDT1
• Immunogen: Recombinant protein corresponding to Human SIDT1. Recombinant protein control fragment (Product #RP-96283).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG