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Invitrogen™ SIAH1 Polyclonal Antibody
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Product Code. 13483907
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Quantity:
100 μL
Unit Size:
100µL
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13483907 100 μL 100µL
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Product Code. 13483907 Supplier Invitrogen™ Supplier No. PA529682

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG. Predicted reactivity: Rat (99%), Zebrafish (97%), Xenopus laevis (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is a member of the seven in absentia homolog family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIAH1
Applications Immunohistochemistry (Paraffin), Western Blot, Proximity Ligation Assay
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene SIAH1
Gene Accession No. Q8IUQ4
Gene Alias AA960570; AA982064; AI853500; E3 ubiquitin-protein ligase SIAH1; E3 ubiquitin-protein ligase SIAH1A; E3 ubiquitin-protein ligase SIAH1B; FLJ08065; h HUMSIAH; hSIAH1; HUMSIAH; mSiah-1a; RING-type E3 ubiquitin transferase SIAH1; RING-type E3 ubiquitin transferase SIAH1A; RING-type E3 ubiquitin transferase SIAH1B; seven in absentia 1A; seven in absentia 1B; seven in absentia homolog 1; Seven in absentia homolog 1a; Seven in absentia homolog 1b; SIAH; siah E3 ubiquitin protein ligase 1; SIAH1; siah-1; Siah1a; Siah-1a; Siah1b; siah-1b; Sinh1a; Sinh1b
Gene Symbols SIAH1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SIAH1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6477
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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