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SHIP Rabbit, anti-Mouse, Unconjugated, Polyclonal, STEMCELL Technologies
Rabbit Polyclonal Antibody
Brand: Stemcell Technologies 60141
This item is not returnable.
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Description
- SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation
- SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway
- This antibody reacts with mouse full-length SHIP protein, 145 kDa, as well as the C-terminal truncated 135, 125, and 110 kDa forms
Specifications
| SHIP | |
| Polyclonal | |
| Rabbit | |
| Primary | |
| Granulocytes and Subsets, Lymphocytes, Myeloid Cells |
| Immunoblot, Immunoprecipitation | |
| Unconjugated | |
| 200 μg | |
| Human, Mouse |
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