Invitrogen™ SH3PXD2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558169

Product Code. 15766051

Description

Immunogen sequence: PDPSGKELDT VPAKGRQNEG KSDSLEKIER RVQALNTVNQ SKKATPPIPS KPPGGFGKTS GTPAVKMRNG VRQVAVRPQS VFVSP Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 88%.

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

Specifications

• Antigen: SH3PXD2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sh3pxd2a
• Gene Alias: 2310014D11Rik; AA589508; Adapter protein TKS5; adaptor protein TKS5; AI256723; AI413738; C230050L11; EG329070; FISH; Five SH3 domain-containing protein; five SH3 domains; Gm5098; KIAA0418; SH3 and PX domain-containing protein 2A; SH3 and PX domains 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Sh3md1; SH3PXD2A; Tks5; TSK5; Tyrosine kinase substrate with five SH3 domains
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14218, 309460, 9644
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O89032, Q5TCZ1
• Gene Symbols: Sh3pxd2a
• Immunogen: Recombinant protein corresponding to Human SH3PXD2A. Recombinant protein control fragment (Product #RP-97054).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG