SH3BP1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA521851

Product Code. 13269888

Description

Recommended positive controls: A549, HeLa, Jurkat, NT2D1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.

Specifications

• Antigen: SH3BP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SH3BP1
• Gene Alias: 3bp1; 3BP-1; ARHGAP43; OTTHUMP00000028981; SH3 domain binding protein 1; SH3 domain-binding protein 1; SH3BP1; SH3-domain binding protein 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23616
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9Y3L3
• Gene Symbols: SH3BP1
• Immunogen: Synthetic peptide corresponding to a region within amino acids 639 and 701 of SH3BP1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG