Invitrogen™ SGSH Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596950

Product Code. 16579781

Description

Immunogen sequence: DNGIPFPSGR TNLYWPGTAE PLLVSSPEHP KRWGQVSEAY VSLLDLTPTI LDWFSIPYPS YAIFGSKTIH LTGRSLLPAL EAEPLWATVF GSQSHHEVTM SYPMRSVQHR HFRLVHNLNF KMPFPIDQDF YVSPTFQDLL NRTTAGQPTG WYKDLRHYYY RARWELYDRS RDPHETQNLA TDPRFAQLLE MLRDQLAKWQ WETHDPWVCA PDGVLEEKLS PQCQPLHNEL; Positive Samples: MCF7, 22Rv1, HepG2, Mouse liver, Mouse testis; Cellular Location: Lysosome.

SGSH is one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.

Specifications

• Antigen: SGSH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGSH
• Gene Alias: 4632406A19Rik; heparan sulfate sulfamidase; heparan sulfate sulfatase; HSS; MPS3A; mucopolysaccharidosis type IIIA; N-sulfoglucosamine sulfohydrolase; N-sulfoglucosamine sulfohydrolase (sulfamidase); N-sulphoglucosamine sulphohydrolase; SFMD; SGSH; Sulfoglucosamine sulfamidase; sulphamidase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27029, 6448, 688293
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.79 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P51688
• Gene Symbols: SGSH
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 273-502 of human SGSH (NP_0001901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG