Invitrogen™ SGK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585237

Product Code. 16382175

Description

Keep as concentrated solution. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (88%), Xenopus laevis (91%), Pig (95%), Rabbit (95%), Chicken (94%), Chimpanzee (100%), Bovine (95%). Positive Control: mouse brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells. SGK plays an important role in cellular stress response and cell survival. SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones. It phosphorylates and negatively regulates pro-apoptotic FOXO3A. SGK1 is thought to play an essential function in nephropathy and cardiovascular development.

Specifications

• Antigen: SGK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGK1
• Gene Alias: serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum and glucocorticoid-dependent protein kinase; serum/glucocorticoid regulated kinase 1; serum/glucocorticoid-regulated kinase 1; Sgk; SGK1; Sgk1 variant i3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20393, 6446
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.38 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O00141, Q9WVC6
• Gene Symbols: SGK1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SGK1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG