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SGC-CBP30, MedChemExpress

Product Code. 16496848
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Product Code. 16496848

Brand: Medchem Express HY15826

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Description

MedChemExpress SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects.

SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects.

Specifications

Chemical Name or Material SGC-CBP30
CAS 1613695-14-9
Color Yellow
Purity Grade Notes Research
Molecular Formula C28H33ClN4O3
Quantity 10 mg
Solubility Information DMSO : ≥ 31 mg/mL (60.90 mM)
SMILES C[C@H](N1CCOCC1)CN2C(CCC3=CC=C(OC)C(Cl)=C3)=NC4=CC(C5=C(C)ON=C5C)=CC=C42
Molecular Weight (g/mol) 509.04
Formula Weight 509.04
Percent Purity 99.06%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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