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Tocris Bioscience™ SGC 6870

Product Code. 18065432
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18065432 5 mg 5mg
18064242 25 mg 25mg
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Product Code. 18065432 Supplier Tocris Bioscience™ Supplier No. 7182/5
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Estimated Shipment: 28-09-2026
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This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price

Potent and selective PRMT6 allosteric inhibitor

SGC 6870 is a potent and selective protein arginine methyltransferase 6 (PRMT6) allosteric inhibitor (IC50 = 77 nM). Exhibits selectivity over all other PRMTs and 23 methyltransferases. In HEK293T cells overexpressing PRMT6, inhibits asymmetric dimethylation of H3R2 (IC50 = 0.8 μM) Negative control SGC 6870N (Cat. No. 7184) also available.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (R)-4-(5-Bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS 2561471-27-8
Quantity 5 mg
Target Protein Arginine Methyltransferase Inhibitors
Molecular Formula C23H21BrN2O2S
Purity 0.98
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