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SFRS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16879904 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16879904 20 μL 20µL
16869904 150 μL 150µL
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Product Code. 16879904 Supplier Proteintech Supplier No. 203711AP20UL

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Description

Rabbit Polyclonal Antibody

The antibody has no cross reaction to SFRS2B.

SFRS2 is necessary for the splicing of pre-mRNA. The protein is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5′- and 3′-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. And it interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5′- and 3′-splice site binding components, U1 snRNP and U2AF. It binds to purine-rich RNA sequences, either 5′-AGSAGAGTA-3′ (S=C or G) or 5′-GTTCGAGTA-3′ and can bind to beta-globin mRNA and commit it to the splicing pathway.

Specifications

Antigen SFRS2
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SRSF2
Gene Accession No. Q01130, Q62093, Q6PDU1
Gene Alias PR264, Protein PR264, SC 35, SC35, SFRS2, SFRS2A, Splicing component, 35 kDa, Splicing factor SC35, SRp30b, SRSF2
Gene Symbols Srsf2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20382, 494445, 6427
Target Species Mouse, Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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