Invitrogen™ SFRS15 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553780

Product Code. 15791711

Description

Immunogen sequence: MHHQVPLPPN GQMPGFGLLP TPPFPPMAQP VIPPTPPVQQ PFQASFQAQN EPLTQKPHQQ EMEVEQPCIQ EVKRHMSDNR KSRSRSASRS PK Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 56%.

The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.

Specifications

• Antigen: SFRS15
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCAF4
• Gene Alias: AA517739; CTD-binding SR-like protein RA4; KIAA1172; pre-mRNA splicing SR protein rA4; SCAF4; serine/arginine-rich splicing factor 15; SFR15; SFRS15; splicing factor serine alanine 15; splicing factor, arginine/serine-rich 15; SRA4; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4; SR-related CTD associated factor 4; SR-related CTD-associated factor 4; Srsf15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57466
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95104
• Gene Symbols: SCAF4
• Immunogen: Recombinant protein corresponding to Human SFRS15. Recombinant protein control fragment (Product #RP-91820).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG