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Invitrogen™ SFRS15 Polyclonal Antibody
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Product Code. 15771771 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15771771 100 μL 100µL
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Product Code. 15771771 Supplier Invitrogen™ Supplier No. PA553838

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PITPPVSIPP PHTPPISIPN STIAGINEDT TKDLSIGNPI PTVVSGARGN AESGDSVKMY GSAVPPAAPT NLPTPPVTQP VSLLGTQGVA PGPVIGLQAP STGLLGARPG LIPLQRPPGM P Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 78%.

The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SFRS15
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SCAF4
Gene Accession No. O95104
Gene Alias AA517739; CTD-binding SR-like protein RA4; KIAA1172; pre-mRNA splicing SR protein rA4; SCAF4; serine/arginine-rich splicing factor 15; SFR15; SFRS15; splicing factor serine alanine 15; splicing factor, arginine/serine-rich 15; SRA4; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4; SR-related CTD associated factor 4; SR-related CTD-associated factor 4; Srsf15
Gene Symbols SCAF4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SFRS15. Recombinant protein control fragment (Product #RP-91821).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57466
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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