Invitrogen™ SF3B2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA560902

Product Code. 15758721

Description

Immunogen sequence: MSTVMSRKGP APELQGVEVA LAPEELELDP MAMTQKYEEH VREQQAQVEK EDFSDMVAEH AAKQKQKKRK AQPQDSRGGS KKYKEFK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Specifications

• Antigen: SF3B2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SF3B2
• Gene Alias: 145kDa; 2610311M13Rik; 2810441F20Rik; B230398H18Rik; Cus1; pre-mRNA splicing factor SF3b 145 kDa subunit; pre-mRNA-splicing factor SF3b 145 kDa subunit; SAP 145; SAP145; SF3b1; SF3B145; SF3b150; SF3B2; spliceosome associated protein 145; spliceosome-associated protein 145; Splicing factor 3B subunit 2; splicing factor 3b, subunit 2; splicing factor 3b, subunit 2, 145kD; splicing factor 3b, subunit 2, 145kDa
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10992
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13435
• Gene Symbols: SF3B2
• Immunogen: Recombinant protein corresponding to Human SF3B2. Recombinant protein control fragment (Product #RP-100756).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG