SETD8 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14063-1-AP-20UL

Product Code. 16832534

Description

Histone methyltransferase that specifically monomethylates ′Lys-20′ of histone H4. H4 ′Lys-20′ monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintece of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.

Specifications

• Antigen: SETD8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT5A
• Gene Alias: H4 K20 HMTase SETD8, KMT5A, Lysine N methyltransferase 5A, PR Set7, PR/SET07, PRSET7, SET07, SET8, SETD8
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387893, 67956
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q2YDW7, Q9NQR1
• Gene Symbols: KMT5A
• Immunogen: SETD8 Fusion Protein Ag5114
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human
• Product Type: Antibody
• Isotype: IgG