Invitrogen™ SERPINB13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589404

Product Code. 16597311

Description

Immunogen sequence: MDSLGAVSTR LGFDLFKELK KTNDGNIFFS PVGILTAIGM VLLGTRGATA SQLEEVFHSE KETKSSRIKA EEKEVIENTE AVHQQFQKFL TEISKLTNDY ELNITNRLFG EKTYLFLQKY LDYVEKYYHA SLEPVDFVNA; Positive Samples: Mouse uterus, Rat uterus; Cellular Location: Cytoplasm.

Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. Differential display was used to identify a novel serpin (headpin or SERPINB13) that is under expressed in squamous cell cancers of the oral cavity. SERPINB13 is expressed in normal oral mucosal tissue, skin, and cultured keratinocytes.

Specifications

• Antigen: SERPINB13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SERPINB13
• Gene Alias: 5430417G24; HaCaT UV-repressible serpin; headpin; HSHUR7SEQ; HUR7; HURPIN; Peptidase inhibitor 13; PI13; PI-13; protease inhibitor 13 (hurpin, headpin); proteinase inhibitor 13; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13; serpin B13; serpin family B member 13; serpin peptidase inhibitor, clade B (ovalbumin), member 13; SERPINB13; UV-B repressed sequence, HUR 7
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 241196, 304690, 5275
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.40 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8CDC0, Q9UIV8
• Gene Symbols: SERPINB13
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SERPINB13 (NP_0365291).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG