Invitrogen™ SERPINA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
11517262	Invitrogen™ PA137070	1 mL
13496777	Invitrogen™ PA532260	500 μL

Description

A suggested positive control is tonsil tissue.

SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.

Specifications

• Antigen: SERPINA3
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.6
• Gene Accession No.: P01011
• Gene ID (Entrez): 12
• Immunogen: Purified human alpha-1-antichymotrypsin.
• Product Type: Antibody

• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: SERPINA3
• Gene Alias: AACT; ACT; alpha-1-antichymotrypsin; Alpha-1-antichymotrypsin His-Pro-less; Cell growth-inhibiting gene 24/25 protein; GIG24; GIG25; Growth inhibiting protein 24; Growth inhibiting protein 25; growth-inhibiting protein 24; growth-inhibiting protein 25; MGC88254; Serine (or cysteine) proteinase inhibitor clade A member 3; serine (or cysteine) proteinase inhibitor, clade A, member 3; serpin A3; serpin family A member 3; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; SERPINA3
• Gene Symbols: SERPINA3
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography