Invitrogen™ Septin 2 Recombinant Rabbit Monoclonal Antibody (24GB1525)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30275486	Invitrogen™ MA557708	100 μL
30275606	Invitrogen™ MA557709	20 μL

Description

Septin 2 Recombinant Monoclonal Antibody for Western Blot, Flow

Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.

Specifications

• Antigen: Septin 2
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: SEPTIN2
• Gene Alias: 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11
• Gene Symbols: SEPTIN2
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Clone: 24GB1525
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P42208, Q15019, Q91Y81
• Gene ID (Entrez): 117515, 18000, 4735
• Immunogen: A synthesized peptide derived from human Septin 2 (aa 250-300).
• Product Type: Antibody