SEPT2 Mouse anti-Human, Mouse, Rat, Clone: 2F3B2, Proteintech

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
16817045	Proteintech 60075-1-IG-20UL	20 μL
16807045	Proteintech 60075-1-IG-150UL	150 μL

Description

Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.

Specifications

• Antigen: SEPT2
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: hNedd5, NEDD 5, NEDD5, SEPT2, SEPT2/septin 2, septin 2, septin2
• Gene Symbols: SEPT2
• Isotype: IgG1
• Purification Method: Caprylic Acid Precipitation
• Product Type: Antibody

• Clone: 2F3B2
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Rat, Mouse, Human
• Gene Accession No.: P42208, Q15019, Q91Y81
• Gene ID (Entrez): 117515, 18000, 4735
• Immunogen: SEPT2 Fusion Protein Ag1946
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SEPT2