Invitrogen™ SEMA6D Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599867

Product Code. 16634115

Description

Antibody detects endogenous levels of total SEMA6D.

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Specifications

• Antigen: SEMA6D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEMA6D
• Gene Alias: 1110067B02Rik; AA409156; D330011G23; FLJ11598; hypothetical protein LOC406272; KIAA1479; KIAA1479FLJ11598; mKIAA1479; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; Sema6d; sema6d protein; semaphorin 6D; semaphorin-6D; wu:fi06a12; wu:fi76a10; zgc:56170
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 214968, 311384, 80031
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q76KF0, Q8NFY4
• Gene Symbols: SEMA6D
• Immunogen: A synthesized peptide derived from human SEMA6D(Accession Q8NFY4), corresponding to amino acid residues T1003-P1053.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG