Invitrogen™ SEMA3E Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585790

Product Code. 16392715

Description

Keep as concentrated solution. Predicted reactivity: Human (88%), Mouse (100%), Rat (97%). Positive Control: mouse brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved approximately 400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling include proteins of the Neuropilin and Plexin families.

Specifications

• Antigen: SEMA3E
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEMA3E
• Gene Alias: 6430702L12; AA408817; coll-5; KIAA0331; mKIAA0331; M-sema H; M-SEMAH; M-SemaK; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; sema H; Sema3e; SEMAH; semaphorin 3E; semaphorin-3E; Semaphorin-H; Semh
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20349
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.86 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P70275
• Gene Symbols: SEMA3E
• Immunogen: Recombinant protein encompassing a sequence within the center region of mouse Semaphorin 3E. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG